BDBM332453 4-(1-(2-chloro- 6-(trifluoro- methyl)benzoyl)- 6-(1,3-dimethyl- ureido)-1H- indazol-3-yl)-3-fluorobenzoic::US10196354, Example 5H::US9745265, 5H
SMILES CNC(=O)N(C)c1ccc2c(nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2c1)-c1ccc(cc1F)C(O)=O
InChI Key InChIKey=PLUSZQBSIICZOQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 332453
Affinity DataIC50: 491nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: 491nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair