BDBM332552 (2E)-3-(4-bromophenyl)-1-[2-(phenylcarbonyl)-2,7-diazaspiro[3.5]non-7-yl]prop-2-en-1-one::US10196369, Compound C7

SMILES Brc1ccc(\C=C\C(=O)N2CCC3(CN(C3)C(=O)c3ccccc3)CC2)cc1

InChI Key InChIKey=WCJGMXLQNVBHDQ-DHZHZOJOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332552   

TargetG-protein coupled receptor 183(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332552((2E)-3-(4-bromophenyl)-1-[2-(phenylcarbonyl)-2,7-d...)
Affinity DataIC50: <5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent