BDBM35052 K00152::US10047093, 8-39::US10392392, Example 8-39::US10875864, EX. 8-39::US9416132, 8-39
SMILES Clc1cccc(c1)-c1cnc2ccc(NC3CCOCC3)nn12
InChI Key InChIKey=OEIWNDGDGDPXIO-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 35052
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMpH: 7.5 T: 2°CAssay Description:Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMT: 2°CAssay Description:These assays are set up in duplicate 50 ul volumes in white, flat bottom 96 well plates. Inhibitors are added to the solution of 1× kinase buff...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China).More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China). More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China).More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:hERG activity assays representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China). More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMT: 2°CAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair