BDBM35909 2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide::2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide (hydroxy flutamide)::2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide(Hydroxyflutamide)::2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide::CHEMBL491::Eulexin::Hydroxyflutamide::OH-flutamide::Sch 16423::US9682960, OH-FLU::cid_91649::hydroxy-flutamide

SMILES CC(C)(O)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI Key InChIKey=YPQLFJODEKMJEF-UHFFFAOYSA-N

Data  9 KI  24 IC50  1 EC50

PDB links: 8 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35909   

TargetAndrogen receptor(Homo sapiens (Human))
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM35909(2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-ph...)
Affinity DataIC50:  7.10E+3nMAssay Description:Displacement of [3H]-DHT from human GST-tagged androgen receptor LBD (627 to 919) expressed in Escherichia coli HB-101 after 15 hrs by liquid scintil...More data for this Ligand-Target Pair
TargetAndrogen receptor(Mus musculus)
Tokyo Medical And Dental University

Curated by ChEMBL
LigandPNGBDBM35909(2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-ph...)
Affinity DataIC50:  370nMAssay Description:Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assayMore data for this Ligand-Target Pair