BDBM389586 N,N-dimethyl-N'-(2-{(E)-2-[4- (methylthio)phenyl]vinyl}quinazolin- 4-yl)ethane-1,2-diamine::US9951029, 88
SMILES CSc1ccc(\C=C\c2nc(NCCN(C)C)c3ccccc3n2)cc1
InChI Key InChIKey=GZTYTAOGJJGFNK-JLHYYAGUSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 389586
Affinity DataIC50: 461nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of FLT3 D835Y (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP-FP...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair
Affinity DataIC50: 6.78E+3nMAssay Description:Inhibition of wildtype FLT3 (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP...More data for this Ligand-Target Pair