Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM389586'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM389586(N,N-dimethyl-N'-(2-{(E)-2-[4- (methylthio)phenyl]v...)
Affinity DataIC50:  340nMAssay Description:Inhibition of FLT3 D835Y (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP-FP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM389586(N,N-dimethyl-N'-(2-{(E)-2-[4- (methylthio)phenyl]v...)
Affinity DataIC50:  461nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM389586(N,N-dimethyl-N'-(2-{(E)-2-[4- (methylthio)phenyl]v...)
Affinity DataIC50:  480nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM389586(N,N-dimethyl-N'-(2-{(E)-2-[4- (methylthio)phenyl]v...)
Affinity DataIC50:  6.78E+3nMAssay Description:Inhibition of wildtype FLT3 (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed