BDBM393279 US9963443, Reference Example 2

SMILES FC1CN(C1)C(=O)C1CCN(CC1)c1cncnc1-c1ccc(F)cc1

InChI Key InChIKey=UTHXOPCOQREWLE-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393279   

TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393279(US9963443, Reference Example 2)
Affinity DataIC50:  8.80nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB