BDBM393286 US9963443, Reference Example 13

SMILES Clc1cnn(c1)-c1ccncc1CC1OCC[C@@H]1NC(=O)C1CCNCC1

InChI Key InChIKey=SENAXRWMKDKRTM-ATNAJCNCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393286   

TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM393286(US9963443, Reference Example 13)
Affinity DataIC50:  20nMAssay Description:For the measurement of CH24H inhibitory activity, using the human CH24H lysate prepared in Experimental Example 2, the amount of 24-HC produced from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent