BDBM425897 US10512644, Compound alpha-6-mPEG3-O-Morphine

SMILES COCCOCCOCCO[C@H]1C=CC2C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45

InChI Key InChIKey=ATTKETJQMFMYKG-UIQNEJLLSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 425897   

TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425897(US10512644, Compound alpha-6-mPEG3-O-Morphine)
Affinity DataKi:  50.7nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425897(US10512644, Compound alpha-6-mPEG3-O-Morphine)
Affinity DataKi:  576nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425897(US10512644, Compound alpha-6-mPEG3-O-Morphine)
Affinity DataKi:  6.18E+3nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425897(US10512644, Compound alpha-6-mPEG3-O-Morphine)
Affinity DataEC50:  270nMAssay Description:Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425897(US10512644, Compound alpha-6-mPEG3-O-Morphine)
Affinity DataEC50:  4.20E+3nMAssay Description:Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent