BDBM430272 US10556883, Compound 11

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)NC2(CC(=O)NO)CN(C2)C(=O)CC(C)(C)C)c2ccccc2n1

InChI Key InChIKey=VOUFFRPOAAEWMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 430272   

TargetInterstitial collagenase(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM430272(US10556883, Compound 11)
Affinity DataIC50: >1.00E+4nMAssay Description:The enzymatic reaction was performed in 384-well microplates with a final volume of 10 ??L containing 1% DMSO. Recombinant Human catalytic domains of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM430272(US10556883, Compound 11)
Affinity DataIC50:  8.20nMAssay Description:Activity of the compounds was investigated using TACE (ADAM17) isolated enzyme. The screening of ADAM17 inhibitors was performed with a profluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent