BDBM444316 US10660898, Example 54

SMILES Cc1c(Cn2c(nc3c(cc(cc23)N2CCOCC2)C(N)=O)C(F)(F)F)cccc1C(F)(F)F

InChI Key InChIKey=ORNWYPZMBXFZMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444316   

TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM444316(US10660898, Example 54)
Affinity DataIC50:  2.51nMAssay Description:PI3Kinase Reaction Buffer was prepared by diluting the stock 1:4 with de-ionized water. Freshly prepared DTT was added at a final concentration of 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent