BDBM450605 2-[6-(1-Acetylpiperidin-4-yl)-4-oxopyrido[3,4-d]pyrimidin-3-yl]-N-[(3-chloro-4-cyanophenyl)methyl]-N-methylacetamide::US10676446, Example 189

SMILES CN(Cc1ccc(C#N)c(Cl)c1)C(=O)Cn1cnc2cnc(cc2c1=O)C1CCN(CC1)C(C)=O

InChI Key InChIKey=MBTDWYFVHQQPOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450605   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM450605(2-[6-(1-Acetylpiperidin-4-yl)-4-oxopyrido[3,4-d]py...)
Affinity DataIC50:  1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent