BDBM474979 US10849901, Compound 29::US10953012, Example 25

SMILES Clc1ccc(cc1)-c1c(Cc2ccccc2)nn2c1[nH]c(cc2=O)-c1ccccc1

InChI Key InChIKey=UOZPNLDGRRPWDX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 474979   

TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474979(US10849901, Compound 29 | US10953012, Example 25)
Affinity DataIC50:  1.5nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase [879-1323](Homo sapiens (Human))
Bioenergenix

US Patent
LigandPNGBDBM474979(US10849901, Compound 29 | US10953012, Example 25)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPAS domain-containing serine/threonine-protein kinase [879-1323](Homo sapiens (Human))
Bioenergenix

US Patent
LigandPNGBDBM474979(US10849901, Compound 29 | US10953012, Example 25)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM474979(US10849901, Compound 29 | US10953012, Example 25)
Affinity DataIC50:  3.30nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In DepthDetails US Patent