BDBM484049 (S)-1-((R)-8-(4'- (aminomethyl)-4- ethoxybiphenyl-3- ylsulfonyl)-l-oxa-8- azaspiro[4.5]decan-3- ylamino)-3-(3-(1,1- difluoro-2- hydroxyethylsulfonyl) phenoxy)propan-2-ol::US10927123, Compound 161

SMILES CCOc1ccc(cc1S(=O)(=O)N1CCC2(C[C@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)C(F)(F)CO)CC1)-c1ccc(CN)cc1

InChI Key InChIKey=POEMYWADWSEZSB-IZLXSDGUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484049   

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484049((S)-1-((R)-8-(4'- (aminomethyl)-4- ethoxybiphenyl-...)
Affinity DataIC50:  2.11E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent