BDBM50002805 (daltroban){4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-phenyl}-acetic acid::BM 13505::BM-13505::CHEMBL71685::Daltroban::{4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-phenyl}-acetic acid
SMILES OC(=O)Cc1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1
InChI Key InChIKey=IULOBWFWYDMECP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50002805
Affinity DataIC50: 37nMAssay Description:In vitro thromboxane A2 antagonistic activity of the compound on U-46619 (0.1 uM) induced contraction of rat aortaMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigradeMore data for this Ligand-Target Pair
TargetThromboxane A2 receptor(Homo sapiens (Human))
Squibb Institute For Medical Research
Curated by PDSP Ki Database
Squibb Institute For Medical Research
Curated by PDSP Ki Database
Affinity DataIC50: 460nMAssay Description:In vitro thromboxane A2 antagonistic activity on aggregation of rabbit platelets induced by U-46,619 (4 uM)More data for this Ligand-Target Pair
TargetThromboxane A2 receptor(Homo sapiens (Human))
Squibb Institute For Medical Research
Curated by PDSP Ki Database
Squibb Institute For Medical Research
Curated by PDSP Ki Database
Affinity DataIC50: 150nMAssay Description:In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human plateletsMore data for this Ligand-Target Pair