BDBM50003795 5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-meth-(E)-ylideneaminooxy]-pentanoic acid::5-[Pyridin-3-yl-(3-trifluoromethyl-phenyl)-methyleneaminooxy]-pentanoic acid::CHEMBL280728::R-68070::ridogrel

SMILES OC(=O)CCCCO\N=C(\c1cccnc1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=GLLPUTYLZIKEGF-HAVVHWLPSA-N

Data  17 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50003795   

TargetThromboxane A2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50003795(5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...)
Affinity DataIC50:  1.28E+3nMAssay Description:In vitro thromboxane receptor antagonist against U-46619 induced aggregation of washed human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50003795(5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of the compound against thromboxane synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50003795(5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...)
Affinity DataIC50:  32nMAssay Description:In vitro TXA2 synthase antagonism through inhibition of collagen induced thromboxane-A2 production in human citrated whole bloodChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50003795(5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50003795(5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...)
Affinity DataKd:  1.26E+3nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50003795(5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...)
Affinity DataKd:  3.98E+3nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole blood.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article