BDBM50005246 1-Phenylpropan-2-amin::1-phenyl-2-aminopropane::1-phenylpropan-2-amine::AMP ASPARTATE::AMPHETAMINE::AMPHETAMINE SULFATE::Amfetamine::Amphetamin::DEXTROAMP SACCHARATE::alpha-methylbenzeneethaneamine::alpha-methylphenylethylamine::amfetaminum::beta-Phenylisopropylamin::beta-aminopropylbenzene::beta-phenylisopropylamine::desoxynorephedrine

SMILES CC(N)Cc1ccccc1

InChI Key InChIKey=KWTSXDURSIMDCE-UHFFFAOYSA-N

Data  47 KI  7 IC50  1 Kd

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50005246   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Nih

Curated by PDSP Ki Database
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)
Affinity DataIC50:  960nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter expressed in rat striatal homogenate after 5 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of noradrenaline transporter in NMRI albino mouse brain assessed as [3H]NA accumulation in hypothalamus after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)
Affinity DataIC50:  200nMAssay Description:Inhibition of [3H]norepinephrine uptake at NET expressed in rat hypothalamic homogenate containing synaptosomes after 5 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory concentration against human cytochrome P450 2A6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 22 member 3(Rattus norvegicus)
Medical College Of Georgia

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)
Affinity DataIC50:  4.20E+4nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in OCT3-expressing HRPE cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A5(Mus musculus)
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50005246(1-Phenylpropan-2-amin | 1-phenyl-2-aminopropane | ...)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibitory concentration against mouse cytochrome P450 2A5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed