BDBM50015004 CHEMBL3262372::US9259422, 7a, R = 2-thienyl- BU08026::US9480684, 7a, R = 2- thienyl- BU08026
SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@]([H])(C1)[C@](C)(O)c1cccs1)ccc3O
InChI Key InChIKey=ZVZIAWYLQBHCMQ-HETHIKCESA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50015004
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -12.6kcal/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl,
pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or
presence ...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]diprenorphine from recombinant human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 34.5nM ΔG°: -10.2kcal/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl,
pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or
presence ...More data for this Ligand-Target Pair
Affinity DataKi: 34.5nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Displacement of [3H]-N/OFQ from recombinant nociceptin opioid receptor (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair