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Found 3 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50015004'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University of Bath

US Patent
LigandPNGBDBM50015004(CHEMBL3262372 | US9259422, 7a, R = 2-thienyl- BU08...)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presence ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University of Bath

US Patent
LigandPNGBDBM50015004(CHEMBL3262372 | US9259422, 7a, R = 2-thienyl- BU08...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University of Bath

US Patent
LigandPNGBDBM50015004(CHEMBL3262372 | US9259422, 7a, R = 2-thienyl- BU08...)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In DepthDetails US Patent