BDBM50017659 2-(Dimethylamino)ethyl p-(butylamino)benzoate::2-(dimethylamino)ethyl 4-(butylamino)benzoate::CHEMBL698::Diaethylaminoaethanol ester der p-butylaminobenzoesaeure::TETRACAINE::p-Butylaminobenzoyl-2-dimethylaminoethanol

SMILES CCCCNc1ccc(cc1)C(=O)OCCN(C)C

InChI Key InChIKey=GKCBAIGFKIBETG-UHFFFAOYSA-N

Data  2 KI  20 IC50  2 Kd

PDB links: 6 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017659   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50017659(2-(Dimethylamino)ethyl p-(butylamino)benzoate | 2-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells at -120 mV holding potential incubated over 5 mins measured at 15 secs interval by Qpatch clamp ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50017659(2-(Dimethylamino)ethyl p-(butylamino)benzoate | 2-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Nav1.7 expressed in CHO-K1 cells at -120 mV holding potential incubated over 5 mins measured at 15 secs interval by Qpatch clamp ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed