BDBM50018174 CHEMBL283109::N-{2-[(2-Acetylamino-propionyl)-hydrazono]-1-benzyl-ethyl}-benzamide

SMILES C[C@H](NC(C)=O)C(=O)NN=CC(Cc1ccccc1)NC(=O)c1ccccc1

InChI Key InChIKey=ZXJNTMWTKAJDGW-FUKCDUGKSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018174   

TargetPapain(Carica papaya)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50018174(CHEMBL283109 | N-{2-[(2-Acetylamino-propionyl)-hyd...)
Affinity DataKi:  500nMpH: 5.0Assay Description:Inhibition of chymotrypsin-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50018174(CHEMBL283109 | N-{2-[(2-Acetylamino-propionyl)-hyd...)
Affinity DataKi:  700nMpH: 5.0Assay Description:Inhibition of papain-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50018174(CHEMBL283109 | N-{2-[(2-Acetylamino-propionyl)-hyd...)
Affinity DataKi:  2.60E+4nMpH: 7.8Assay Description:Inhibition of chymotrypsin-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50018174(CHEMBL283109 | N-{2-[(2-Acetylamino-propionyl)-hyd...)
Affinity DataKi:  3.10E+4nMpH: 7.0Assay Description:Initial rate of reaction between Chymotrypsinogen and BzArg p-nitro-anilide in the presence of 400 microM of the compound at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50018174(CHEMBL283109 | N-{2-[(2-Acetylamino-propionyl)-hyd...)
Affinity DataKi:  4.80E+4nMpH: 5.0Assay Description:Inhibition of papain-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 5.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed