BDBM50018179 2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophene-6-carboxylic acid::CHEMBL22542::Imitrodast

SMILES OC(=O)C1=Cc2sc(Cn3ccnc3)cc2CC1

InChI Key InChIKey=KRBSZXUPPSXPAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50018179   

TargetThromboxane-A synthase(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50018179(2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...)
Affinity DataIC50:  13nMAssay Description:Inhibition of thromboxane A2 synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50018179(2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...)
Affinity DataIC50:  6nMAssay Description:Inhibition of platelet microsomal thromboxane A synthetase in rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50018179(2-Imidazol-1-ylmethyl-4,5-dihydro-benzo[b]thiophen...)
Affinity DataIC50:  13nMAssay Description:Inhibition of platelet microsomal thromboxane A2 synthetase in rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed