BDBM50018612 4-(4-Imidazol-1-yl-phenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one::CHEMBL30358

SMILES O=C1NN=C(C2CCCCC12)c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=FXPSDQOKDIWBGU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018612   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018612(4-(4-Imidazol-1-yl-phenyl)-4a,5,6,7,8,8a-hexahydro...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018612(4-(4-Imidazol-1-yl-phenyl)-4a,5,6,7,8,8a-hexahydro...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018612(4-(4-Imidazol-1-yl-phenyl)-4a,5,6,7,8,8a-hexahydro...)
Affinity DataIC50:  3.80E+5nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018612(4-(4-Imidazol-1-yl-phenyl)-4a,5,6,7,8,8a-hexahydro...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018612(4-(4-Imidazol-1-yl-phenyl)-4a,5,6,7,8,8a-hexahydro...)
Affinity DataIC50:  5.50E+5nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed