BDBM50018613 6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3-one::CHEMBL31105

SMILES Cc1cc(=O)[nH]nc1-c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=JHCQIYAUCIHYNU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50018613   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50:  6.60E+5nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of cAMP PDE III enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50:  6.60E+5nMAssay Description:Inhibition of cAMP PDE I enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition cGMP PDE I enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018613(6-(4-Imidazol-1-yl-phenyl)-5-methyl-2H-pyridazin-3...)
Affinity DataIC50:  2.10E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed