BDBM50018614 5-Ethyl-6-(4-imidazol-1-yl-phenyl)-4,5-dihydro-2H-pyridazin-3-one::CHEMBL30362

SMILES CCC1CC(=O)NN=C1c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=IFMSLEJMFHOWPL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018614   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018614(5-Ethyl-6-(4-imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018614(5-Ethyl-6-(4-imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018614(5-Ethyl-6-(4-imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018614(5-Ethyl-6-(4-imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018614(5-Ethyl-6-(4-imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed