BDBM50018616 6-(4-Imidazol-1-yl-phenyl)-2-methyl-4,5-dihydro-2H-pyridazin-3-one::CHEMBL31112

SMILES CN1N=C(CCC1=O)c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=SLWHZJYHEKCTQX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018616   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018616(6-(4-Imidazol-1-yl-phenyl)-2-methyl-4,5-dihydro-2H...)
Affinity DataIC50:  3.70E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018616(6-(4-Imidazol-1-yl-phenyl)-2-methyl-4,5-dihydro-2H...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018616(6-(4-Imidazol-1-yl-phenyl)-2-methyl-4,5-dihydro-2H...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018616(6-(4-Imidazol-1-yl-phenyl)-2-methyl-4,5-dihydro-2H...)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018616(6-(4-Imidazol-1-yl-phenyl)-2-methyl-4,5-dihydro-2H...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed