BDBM50018618 6-(4-Benzoimidazol-1-yl-phenyl)-4,5-dihydro-2H-pyridazin-3-one::CHEMBL30402

SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1cnc2ccccc12

InChI Key InChIKey=DGILEKCXNQODOP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018618   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018618(6-(4-Benzoimidazol-1-yl-phenyl)-4,5-dihydro-2H-pyr...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018618(6-(4-Benzoimidazol-1-yl-phenyl)-4,5-dihydro-2H-pyr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018618(6-(4-Benzoimidazol-1-yl-phenyl)-4,5-dihydro-2H-pyr...)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018618(6-(4-Benzoimidazol-1-yl-phenyl)-4,5-dihydro-2H-pyr...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018618(6-(4-Benzoimidazol-1-yl-phenyl)-4,5-dihydro-2H-pyr...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed