BDBM50018620 6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one::CHEMBL58728

SMILES O=c1ccc(n[nH]1)-c1ccc(cc1)-c1ncc[nH]1

InChI Key InChIKey=ZUOGTJVNQLGUKO-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50018620   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  1.90E+5nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  4.60E+5nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  1.90E+5nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  3.30E+5nMAssay Description:Inhibition cGMP PDE I enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  3.30E+5nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  4.60E+5nMAssay Description:Inhibition of cAMP PDE I enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50018620(6-[4-(1H-Imidazol-2-yl)-phenyl]-2H-pyridazin-3-one...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed