BDBM50022831 6,7-Dimethyl-pteridine-2,4-diamine::CHEMBL29143
SMILES Cc1nc2nc(N)nc(N)c2nc1C
InChI Key InChIKey=NBGMCAGDMQPEBF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50022831
Affinity DataKi: 44nMAssay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 8More data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Inhibition constant for Tyr31-dihydrofolate reductase (DHFR)-NADPH-Compound complexMore data for this Ligand-Target Pair
Affinity DataKi: 9.10E+3nMAssay Description:Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKoff: 6.80E+6s-1Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKon: 35M-1s-1Assay Description:Binding constant(Ki) to dihydrofolate reductase (DHFR) Val -31 was determinedMore data for this Ligand-Target Pair
Affinity DataKd: 3.90E+3nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKoff: 1.20E+7s-1Assay Description:Association constant (Kon) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKon: 25M-1s-1Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8More data for this Ligand-Target Pair