BDBM50029775 (R)-(+)-N-{3-[5-(4-fluorophenoxy)furan-2-yl]-1-methylprop-2-ynyl}-N-hydroxyurea::(S)-(-)-N-{3-[5-(4-fluorophenoxy)furan-2-yl]-1-methylprop-2-ynyl}-N-hydroxyurea::A-78773::CHEMBL59598::N-{3-[5-(4-fluorophenoxy)-2-furyl]-1-methylprop-2-ynyl}-N-hydroxyurea::N-{3-[5-(4-fluorophenoxy)-2-furyl]-1-methylprop-2-ynyl}-N-hydroxyurea(A-78773)::N-{3-[5-(4-fluorophenoxy)furan-2-yl]-1-methylprop-2-ynyl}-N-hydroxyurea
SMILES CC(C#Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O
InChI Key InChIKey=OLZHFFKRBCZHHT-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50029775
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataIC50: 298nMAssay Description:Inhibition of 5-lipoxygenase mediated conversion of [14C]-arachidonic acid to leukotrienes in RBL-2H3 cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair