BDBM50029775 (R)-(+)-N-{3-[5-(4-fluorophenoxy)furan-2-yl]-1-methylprop-2-ynyl}-N-hydroxyurea::(S)-(-)-N-{3-[5-(4-fluorophenoxy)furan-2-yl]-1-methylprop-2-ynyl}-N-hydroxyurea::A-78773::CHEMBL59598::N-{3-[5-(4-fluorophenoxy)-2-furyl]-1-methylprop-2-ynyl}-N-hydroxyurea::N-{3-[5-(4-fluorophenoxy)-2-furyl]-1-methylprop-2-ynyl}-N-hydroxyurea(A-78773)::N-{3-[5-(4-fluorophenoxy)furan-2-yl]-1-methylprop-2-ynyl}-N-hydroxyurea

SMILES CC(C#Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O

InChI Key InChIKey=OLZHFFKRBCZHHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029775   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50029775((R)-(+)-N-{3-[5-(4-fluorophenoxy)furan-2-yl]-1-met...)
Affinity DataIC50:  298nMAssay Description:Inhibition of 5-lipoxygenase mediated conversion of [14C]-arachidonic acid to leukotrienes in RBL-2H3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed