BDBM50030727 4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid benzoylamide::CHEMBL279629::CHEMBL97539::L-159,913::L-159913

SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1

InChI Key InChIKey=JVOGASLNIGJLLS-UHFFFAOYSA-N

Data  3 KI  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50030727   

TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50030727(4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,...)
Affinity DataIC50:  300nMAssay Description:In vitro binding affinity of the compound towards Angiotensin II receptor, type 2 to displace 125I[Sar,Ile] from rat brain tissue preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50030727(4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,...)
Affinity DataIC50:  0.330nMAssay Description:In vitro binding affinity of the compound towards Angiotensin II receptor, type 1 to displace 125I[Sar,Ile] from rat adrenal tissue preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50030727(4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,...)
Affinity DataIC50:  0.310nMAssay Description:In vitro binding affinity of the compound towards Angiotensin II receptor, type 1 to displace 125I[Sar,Ile] from rat brain tissue preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50030727(4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,...)
Affinity DataIC50:  0.550nMAssay Description:In vitro binding affinity of the compound towards angiotensin-1 receptor to displace 125I[Sar,Ile] from rabbit brain tissue preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50030727(4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,...)
Affinity DataIC50:  270nMAssay Description:In vitro binding affinity of the compound towards Angiotensin II receptor, type 2 to displace 125I[Sar,Ile] from rat adrenal tissue preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50030727(4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,...)
Affinity DataIC50:  0.430nMAssay Description:Displacement of 125I[Sar,Ile] from rabbit aorta membrane Angiotensin II receptor type 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50030727(4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,...)
Affinity DataIC50:  0.5nMAssay Description:In vitro binding affinity of the compound towards angiotensin-1 receptor to displace 125I[Sar,Ile] from rabbit adrenal tissue preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50030727(4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,...)
Affinity DataIC50:  0.550nMAssay Description:In vitro binding affinity of the compound towards angiotensin-1 receptor to displace 125I[Sar,Ile] from rabbit brain tissue preparationMore data for this Ligand-Target Pair
In DepthDetails Article