BDBM50037037 5,7-Dimethyl-2-methylamino-4-pyridin-3-ylmethyl-benzothiazol-6-ol::CHEMBL105139
SMILES CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1
InChI Key InChIKey=IONAQTGMWFXHIX-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50037037
Affinity DataIC50: 230nMAssay Description:Tested for inhibitory activity against 5-lipoxygenase in microsome of RBL-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against thromboxane A2 synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition constant against arachidonate 5-lipoxygenase More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Tested for inhibitory activity against leukotriene B4 (LTB4) receptor in human neutrophilsMore data for this Ligand-Target Pair