BDBM50038268 2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimidin-4-one::CHEMBL134613

SMILES NC1NC(=O)C2=CC=CN(Cc3ccccc3)C2=N1

InChI Key InChIKey=BIAHJMNFQFOCFO-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50038268   

TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  700nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  3.70E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  7.30E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  1.70E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed