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Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50038268'
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  700nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  3.70E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  7.30E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  1.70E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed