BDBM50041057 2-[3-(3,4-Difluoro-phenyl)-2-mercaptomethyl-butyrylamino]-3-(4-hydroxy-phenyl)-propionic acid::CHEMBL11607

SMILES CC(C(CS)C(=O)NC(Cc1ccc(O)cc1)C(O)=O)c1ccc(F)c(F)c1

InChI Key InChIKey=KKGOJCSRJIGKPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041057   

TargetAngiotensin-converting enzyme(Mus musculus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50041057(2-[3-(3,4-Difluoro-phenyl)-2-mercaptomethyl-butyry...)
Affinity DataIC50:  4.5nMAssay Description:Inhibitory potency against angiotensin converting enzyme by displacement of [3H]-trandolaprilate binding in mouse lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50041057(2-[3-(3,4-Difluoro-phenyl)-2-mercaptomethyl-butyry...)
Affinity DataIC50:  5.20nMAssay Description:In vivo inhibitory potency against neutral endopeptidase by displacement of [3H]-HACBOGly binding in mouse kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed