BDBM50041127 6-Thiophen-2-yl-5H-[1,3]dioxolo[4,5-g]quinolin-8-one::CHEMBL14540

SMILES Oc1cc(nc2cc3OCOc3cc12)-c1cccs1

InChI Key InChIKey=NMFTWAYYGHNSDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041127   

TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50041127(6-Thiophen-2-yl-5H-[1,3]dioxolo[4,5-g]quinolin-8-o...)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041127(6-Thiophen-2-yl-5H-[1,3]dioxolo[4,5-g]quinolin-8-o...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed