BDBM50048066 CHEMBL1316265::OMDM2::US10300048, Compound OMDM-2

SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CO)Cc1ccc(O)cc1

InChI Key InChIKey=ICDMLAQPOAVWNH-HAAQQRBASA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50048066   

TargetFatty acid-binding protein, liver(Mus musculus (Mouse))
Avanti Polar Lipids

LigandPNGBDBM50048066(CHEMBL1316265 | OMDM2 | US10300048, Compound OMDM-...)
Affinity DataKi:  40nMAssay Description:The following fluorescent ligand displacement assays at 24 C were used to further confirm and/or determine if the cytosolic lipidic ligand "chaperon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
UNIVERSITAT BERN

US Patent
LigandPNGBDBM50048066(CHEMBL1316265 | OMDM2 | US10300048, Compound OMDM-...)
Affinity DataIC50:  3.90E+3nMAssay Description:Screening for AEA cellular uptake inhibition was performed in a semi-automated procedure: Pipetting and washing steps were performed by a Biomek3000 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
UNIVERSITAT BERN

US Patent
LigandPNGBDBM50048066(CHEMBL1316265 | OMDM2 | US10300048, Compound OMDM-...)
Affinity DataIC50:  2.34E+4nMAssay Description:Hydrolysis of [3H]-AEA by FAAH was determined as previously described in cell homogenates of U937 cells (0.18 mg protein) (Omeir et al., 1999, Bioche...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
UNIVERSITAT BERN

US Patent
LigandPNGBDBM50048066(CHEMBL1316265 | OMDM2 | US10300048, Compound OMDM-...)
Affinity DataIC50:  2.33E+4nMAssay Description:Inhibition of FAAH-mediated [ethanol-amine-1-3H]AEA hydrolysis in human U937 cells preincubated for 15 mins measured 15 mins post AEA addition by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed