BDBM50050071 CHEMBL3317729
SMILES Clc1ccc(cc1)-c1c(sc2ncccc12)S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=HRULVFZMZKQTBK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50050071
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membrane preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Negative allosteric modulation of mGlu5 receptor in primary E17 rat embryo neuron assessed as ca2+ level by fluo-4/AM assayMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of mGluR5 in rat embryo neuronal culture assessed as calcium level by Fluo-4/AM dye based fluorometryMore data for this Ligand-Target Pair