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Found 4 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50050071'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50050071(CHEMBL3317729)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50050071(CHEMBL3317729)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50050071(CHEMBL3317729)
Affinity DataIC50:  46nMAssay Description:Negative allosteric modulation of mGlu5 receptor in primary E17 rat embryo neuron assessed as ca2+ level by fluo-4/AM assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50050071(CHEMBL3317729)
Affinity DataIC50:  46nMAssay Description:Inhibition of mGluR5 in rat embryo neuronal culture assessed as calcium level by Fluo-4/AM dye based fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed