BDBM50056315 CHEBI:17558::Quercitrin

SMILES C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=OXGUCUVFOIWWQJ-HQBVPOQASA-N

Data  1 KI  10 IC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50056315   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataKi:  3.96E+4nMAssay Description:Non competitive inhibition of sEH (unknown origin) using varying levels of PHOME as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (strain A/USSR/90/1977 H1N1))
Freie Universitaet Berlin

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibition of influenza A virus (A/California/07/2009(H1N1)) pdm09 neuraminidase using MUNANA substrate pre-incubated for 30 mins before substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate pretreated for 5 mins followed by substrate addition measured over 30 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of Pretoria

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGenome polyprotein(Dengue virus)
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of dengue virus NS5 RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of sEH (unknown origin) assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate measured after 40 mins by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  6.31E+4nMAssay Description:Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of OATP2B1 mediated DBF uptake using DBF as fluorescent substrate in...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuraminidase(Influenza A virus (strain A/USSR/90/1977 H1N1))
Freie Universitaet Berlin

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.21E+5nMAssay Description:Inhibition of influenza A virus (A/Perth/16/2009(H3N2)) neuraminidase using MUNANA substrate pre-incubated for 30 mins before substrate addition by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Korea Institute Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50056315(CHEBI:17558 | Quercitrin)
Affinity DataIC50:  1.67E+5nMAssay Description:Inhibition of HIV1 recombinant integrase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed