BDBM50058053 CHEMBL3330804::US9260448, 6
SMILES Clc1cccc(c1)-n1cnc2c(csc2c1=O)-c1ccccc1
InChI Key InChIKey=YZEGKECIXQTPKF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50058053
Affinity DataIC50: 374nMAssay Description:Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Cells of Chem3 Cell Line (HTS145C:Millipore) in which mGluR1 was stably expressed were adjusted to a density of 2×106/ml. 50 μl of the cells wer...More data for this Ligand-Target Pair