Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50058053'
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Korea Institute of Science and Technology
US Patent
Korea Institute of Science and Technology
US Patent
Affinity DataIC50: 58nMAssay Description:Cells of Chem3 Cell Line (HTS145C:Millipore) in which mGluR1 was stably expressed were adjusted to a density of 2×106/ml. 50 μl of the cells wer...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Korea Institute of Science and Technology
US Patent
Korea Institute of Science and Technology
US Patent
Affinity DataIC50: 374nMAssay Description:Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...More data for this Ligand-Target Pair