BDBM50072288 3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan-3-ylmethyl)-benzamidine; compound with acetic acid::CHEMBL102134

SMILES NC(=N)c1cccc(C[C@@H]2[C@H]3CCC[C@@H]3OC2=O)c1

InChI Key InChIKey=ZWVDMTZPWFZXOO-UPJWGTAASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072288   

TargetChymotrypsin-C(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for the inhibition of ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50072288(3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed