BDBM50073190 CHEMBL3408213::US11471446, Compound DBA-11
SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
InChI Key InChIKey=LBFYQISQYCGDDW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50073190
Affinity DataKi: 9nMAssay Description:Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Inhibition of human full length PKCtheta using histone H1 as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scintillation counting...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataKi: 231nMAssay Description:Inhibition of human GSKalpha S449A mutant (2 to 3nd residues) using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE as substrate incubated for 40 mins in presence of ...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of South Australia
Curated by ChEMBL
University Of South Australia
Curated by ChEMBL
Affinity DataKi: 345nMAssay Description:Inhibition of human GSKbeta H350L mutant (2 to 3nd residues) using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE as substrate incubated for 40 mins in presence of [...More data for this Ligand-Target Pair