BDBM50073587 CHEMBL3408947::US10358436, Example A185::US20230365537, Example CFI-400495::US9907800, Example A185
SMILES COc1ccc2NC(=O)[C@@]3(C[C@H]3c3ccc4c(\C=C\c5ccc(CN6C[C@H](C)O[C@H](C)C6)cc5)n[nH]c4c3)c2c1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50073587
Affinity DataKi: 0.260nMAssay Description:Competitive binding to PLK4 (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using DBF as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using BFC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of AURKA (unknown origin) by FRET analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Inhibition of PLK4 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 510nMAssay Description:Inhibition of AURKA (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 117nMAssay Description:Inhibition of TIE2 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 84nMAssay Description:Inhibition of TRKA (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 88nMAssay Description:Inhibition of TRKB (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of TIE2 (unknown origin) by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of TRKA (unknown origin) by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of PLK4 (unknown origin) by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of TRKB (unknown origin) by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 940nMAssay Description:Inhibition of CYP2C9 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair