BDBM50096968 CHEMBL3580919
SMILES COc1ccc2[nH]cc(CCc3n[nH]c(=O)o3)c2c1
InChI Key InChIKey=RRCYFTXMWOJGMP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50096968
Affinity DataKi: 4nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [125l]-lodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Displacement of [125l]-lodomelatonin from human MT1 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-1 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataEC50: 326nMAssay Description:Agonist activity at human melatonin receptor-1 transfected in CHO cell membranes after 1 hr by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Agonist activity at human melatonin receptor-2 transfected in CHO cell membranes after 1 hr by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)
Curated by ChEMBL
Affinity DataEC50: 48nMAssay Description:Agonist activity at human recombinant melatonin receptor-1 expressed in CHO cells assessed as effect on impedance by cellular dielectric spectroscopyMore data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Agonist activity at human recombinant melatonin receptor-2 expressed in CHO cells assessed as decrease of cAMP level after 10 mins by HTRF assayMore data for this Ligand-Target Pair