BDBM50096968 CHEMBL3580919

SMILES COc1ccc2[nH]cc(CCc3n[nH]c(=O)o3)c2c1

InChI Key InChIKey=RRCYFTXMWOJGMP-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50096968   

TargetMelatonin receptor type 1B(Homo sapiens (Human))
Iqm-Csic

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataKi:  4nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Iqm-Csic

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataKi:  4nMAssay Description:Displacement of [125l]-lodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataKi:  35nMAssay Description:Displacement of [125l]-lodomelatonin from human MT1 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataKi:  35nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-1 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataEC50:  326nMAssay Description:Agonist activity at human melatonin receptor-1 transfected in CHO cell membranes after 1 hr by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Iqm-Csic

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human melatonin receptor-2 transfected in CHO cell membranes after 1 hr by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Consejo Superior De Investigaciones Cient�Ficas (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human recombinant melatonin receptor-1 expressed in CHO cells assessed as effect on impedance by cellular dielectric spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Iqm-Csic

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human recombinant melatonin receptor-2 expressed in CHO cells assessed as decrease of cAMP level after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed