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Found 4 Enz. Inhib. hit(s) with Target = 'Melatonin receptor type 1B' and Ligand = 'BDBM50096968'
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Iqm-Csic

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataKi:  4nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human melatonin receptor-2 transfected in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Iqm-Csic

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataKi:  4nMAssay Description:Displacement of [125l]-lodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Iqm-Csic

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human melatonin receptor-2 transfected in CHO cell membranes after 1 hr by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Iqm-Csic

Curated by ChEMBL
LigandPNGBDBM50096968(CHEMBL3580919)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human recombinant melatonin receptor-2 expressed in CHO cells assessed as decrease of cAMP level after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed