BDBM50102311 3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6,7-dimethyl-pyrazolo[1,5-a]pyrimidine::CHEMBL331921

SMILES Cc1cnc2c(c(nn2c1C)-c1ccc(cc1)S(C)(=O)=O)-c1ccc(F)cc1

InChI Key InChIKey=WHGZGEFGZXHTST-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102311   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50102311(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6...)
Affinity DataIC50:  12nMAssay Description:Inhibition of COX-2 in human 143982 cells using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed