BDBM50105085 17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alpha,14-triol::CHEMBL895::N-cyclobutylmethyl-4,5alpha-epoxy-3,6alpha,14-morphinantriol::NALBUPHINE::US10231963, Table B.1::US10512644, Compound Nalbuphine::US11534436, Compound Table B.1::US9233167, Nalbuphine::US9656961, Example 00118::USRE49340, Rank 9
SMILES O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CCC1)c45
InChI Key InChIKey=NETZHAKZCGBWSS-CEDHKZHLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50105085
Affinity DataKi: 14.3nMAssay Description:Specific binding is determined by subtraction of the cpm bound in the presence of 50-100× excess of cold ligand. Binding data assays were analyzed us...More data for this Ligand-Target Pair
Affinity DataKi: 29.9nMAssay Description:Specific binding is determined by subtraction of the cpm bound in the presence of 50-100× excess of cold ligand. Binding data assays were analyzed us...More data for this Ligand-Target Pair
Affinity DataKi: 319nMAssay Description:Specific binding is determined by subtraction of the cpm bound in the presence of 50-100× excess of cold ligand. Binding data assays were analyzed us...More data for this Ligand-Target Pair
Affinity DataIC50: 752nMpH: 7.4 T: 2°CAssay Description:Test compound and/or vehicle was preincubated with the cell membranes and 3 uM GDP in modified HEPES buffer (pH 7.4) for 20 minutes, followed by addi...More data for this Ligand-Target Pair
Affinity DataEC50: 25.1nMpH: 7.4 T: 2°CAssay Description:Test compound and/or vehicle was preincubated with the cell membranes and 3 uM GDP in modified HEPES buffer (pH 7.4) for 20 minutes, followed by addi...More data for this Ligand-Target Pair